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- Ikaros (found in: Products)
- Neon (found in: Data Management)
- MetaSystems Germany (found in: Contact)
- MetaSystems Italy (found in: Contact)
- MetaSystems Asia (found in: Contact)
- MetaSystems USA (found in: Contact)
- MetaSystems India (found in: Contact)
- MetaSystems Probes Germany (found in: Contact)
- Omnibus Bio-Medical Systems Inc. (found in: Contact)
- MetaSystems LatAm (found in: Contact)
- MetaSystems China (Taizhou) Co. Ltd. (found in: Contact)
- MetaSystems Japan (found in: Contact)
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MetaSystems Sustainability Report 2023 (found in: Certificates, Documents and Forms)PDF:
Certificate ISO 13485:2016 (MetaSystems USA) (found in: Certificates, Documents and Forms)PDF:
Ikaros (found in: Product Brochures)PDF:
MetaSystems Italy Codice Etico [Italian version] (found in: Certificates, Documents and Forms)PDF:
White Paper: Smart Karyogram Creation with Ikaros (found in: White Papers)PDF:
MetaSystems Italy Code of Ethics [English version] (found in: Certificates, Documents and Forms)PDF:
MetaSystems Italy Modello Trasparenza (Sunshine Act) (found in: Certificates, Documents and Forms)PDF:
MetaSystems Italy Whistleblowing Procedure (found in: Certificates, Documents and Forms)PDF:
MetaSystems Italy Quality Policy (found in: Certificates, Documents and Forms)PDF:
Brochure: Customizations for Biodosimetry (found in: Customizations)PDF:
Coming Soon: Ikaros 7 (found in: Product Brochures)- MetaSystems Sustainability Report 2023 (found in: News)
- High-ranking Visitors at MetaSystems (found in: News)
- MetaSystems Announces Grant of US Patent for AI based Chromosome Analysis (found in: News)
- 'Phishing' Attack on MetaSystems Accounts (found in: News)
- MetaSystems Distributor Meeting 2022 (found in: News)
- The MetaSystems Year 2022 (found in: News)
- Collaboration with MLL on AI-based Karyotyping (found in: News)
- MetaSystems Japan (found in: News)
- MetaSystems at GfH 2025 (found in: News)
- MetaSystems and Märzhäuser Wetzlar donate state-of-the-art medical equipment to Ukrainian children's clinic (found in: News)
- Critical role of somatostatin receptor 2 in the vulnerability ofthe central noradrenergic system: new aspects on Alzheimer's disease. (found in: Publications)
- Systematic genome-wide screens of gene function. (found in: Publications)
- Automated scoring of Sperm Hy-Liter™-stained spermatozoa by the MetaSystems Metafer image analysis software system in sexual assault specimens. (found in: Publications)
- Combined karyotyping, CGH and m-FISH analysis allows detailed characterization of unidentified chromosomal rearrangements in Merkel cell carcinoma (found in: Publications)
- High concordance between immunohistochemistry and fluorescence in situ hybridization testing for HER2 status in breast cancer requires a normalized IHC scoring system (found in: Publications)
- Chromosomal rearrangements in post-Chernobyl papillary thyroid carcinomas: evaluation by spectral karyotyping and automated interphase FISH. (found in: Publications)
- Automated metaphase finding: an assessment of the efficiency of the METAFER2 system in routine mutagenicity assay (found in: Publications)
- Molecular cytogenetic characterization of the mouse cell line WMP2 by spectral karyotyping and multicolor banding applying murine probes. (found in: Publications)
- Reliable and sensitive identification of occult tumor cells usingthe improved rare event imaging system. (found in: Publications)
- An Evaluation of the Effectiveness of a Semi-automatic MetaphaseLocating and On-screen Karyotyping System. (found in: Publications)
- Karyotyping of human synaptonemal complexes by cenM-FISH (found in: Publications)
- Automated scoring of lymphocyte micronuclei by the MetaSystems Metaferimage cytometry system and its application in studies of human mutagensensitivity and biodosimetry of genotoxin exposure. (found in: Publications)
- Comparaison de systèmes d'analyse d'images cytologiques en dosimétrie biologique (FRENCH) (found in: Publications)
- Analysis of HER2 gene amplification using an automated fluorescence in situ hybridization signal enumeration system. (found in: Publications)
- Sesamol ameliorates radiation induced DNA damage in hematopoietic system of whole body γ-irradiated mice. (found in: Publications)
- Chromothripsis-like chromosomal rearrangements induced by ionizing radiation using proton microbeam irradiation system. (found in: Publications)
- Evaluation of chromosomal aberrations induced by 188Re-dendrimer nanosystem on B16f1 melanoma cells. (found in: Publications)
- CytoRADx: A High-Throughput, Standardized Biodosimetry Diagnostic System Based on the Cytokinesis-Block Micronucleus Assay. (found in: Publications)
- Update WIBU Runtime (found in: Security Updates)
- Security leak Ripple20 and MetaSystems devices (found in: Security Updates)
- Log4j Security Gap (found in: Security Updates)
- Metafer (found in: Products)
- Carl Zeiss (Shanghai) Co. Ltd. (found in: Contact)
- Attieh Medico (found in: Contact)
- Carl Zeiss NV-NA (found in: Contact)
- Werfen S.A.U. (found in: Contact)
- Carl Zeiss Iberia (found in: Contact)
PDF:
Smart Karyogram Creation (found in: Product Brochures)PDF:
White Paper: Customization Package Sperm Detection (found in: White Papers)PDF:
Metafer (found in: Product Brochures)PDF:
Case and Image Data Management (found in: Product Brochures)PDF:
Brochure: Customization Package Sperm Detection (found in: Customizations)- Product Brochures (found in: Downloads)
- White Papers (found in: Downloads)
- Customizations (found in: Downloads)
- About
- Downloads
- Press / Media Contact
- Manuals (found in: Certificates, Documents and Forms)
- Lieferkettensorgfaltspflicht (found in: About)
- Two-day Hands-on FISH Workshop (found in: News)
- Middle East Meeting 2024 (found in: News)
- Greetings from Nijmegen, NL (found in: News)
- Impressions of the TGA 2024 (found in: News)
- Metafer and XRNA Probes Reveal Incidence for Italy's Covid-19 Patient Zero (found in: News)
- Log4j Security Gap (found in: News)
- 1,000th SlideFeeder x80 (found in: News)
- Technical Training at Headquarters (found in: News)
- Hands-on FISH Workshop (found in: News)
- Outlook for 2023 (found in: News)
- Greetings from the U.S. Applications and Support Team (found in: News)
- Training in Buenos Aires (found in: News)
- Successful Installation at Laboratorios Carpermor (found in: News)
- Jahrestagung der Deutschen Gesellschaft für Humangenetik (found in: News)
- 45th Traces Workshop (found in: News)
- European Human Genetics Conference (found in: News)
- Meeting on Chromosomes (found in: News)
- Annual Clinical Genetics Meeting (found in: News)
- International Workshop on Cancer Genetic and Cytogenetic Diagnostics (found in: News)
- 2025 Children’s Oncology Group Workshop (found in: News)
- European Cytogenetics Conference (found in: News)
- Great Lakes Genomics Conference (found in: News)
- European Academy of Forensic Science (found in: News)
- Tumour Genetics Symposium 2025 (found in: News)
- Southeast Regional Genetics Group (found in: News)
- The micronucleus assay in radiation accidents (found in: Publications)
- Acute neuroinflammation in a clinically relevant focal cortical ischemicstroke model in rat: longitudinal positron emission tomography andimmunofluorescent tracking. (found in: Publications)
- Recurrent genomic instability of chromosome 1q in neural derivativesof human embryonic stem cells. (found in: Publications)
- An automated scoring procedure for the micronucleus test by image analysis (found in: Publications)
- Radiosensitivity detected by the micronucleus test is not generally increased in sporadic prostate cancer patients. (found in: Publications)
- Correlation between aneuploidy, apoptotic markers and DNA fragmentationin spermatozoa from normozoospermic patients. (found in: Publications)
- Automated detection of irradiated food with the comet assay. (found in: Publications)
- Automated detection of irradiated food with the Comet assay. (found in: Publications)
- The micronucleus assay as a biological dosimeter of in vivo ionisingradiation exposure. (found in: Publications)
- Time-saving in biological dosimetry by using the automatic metaphase finder Metafer2 (found in: Publications)
- Automated micronucleus (MN) scoring for population triage in caseof large scale radiation events. (found in: Publications)
- Heterogeneity of BCL6 rearrangements in nodular lymphocyte predominant Hodgkin's lymphoma (found in: Publications)
- Combining M-FISH and Quantum Dot technology for fast chromosomalassignment of transgenic insertions. (found in: Publications)
- Spontaneous rates of sex chromosomal aneuploidies in sperm and offspring of mice: a validation of the detection of aneuploid sperm by fluorescence in situ hybridization (found in: Publications)
- Unequivocal identification of disseminated tumor cells in the bone marrow by combining immunological and genetic approaches–functional and prognostic information. (found in: Publications)
- Disseminated tumour cells in the bone marrow - chances and consequences of microscopical detection methods (found in: Publications)
- Imaging of a clinically relevant stroke model: glucose hypermetabolismrevisited. (found in: Publications)
- Are mouse lens epithelial cells more sensitive to γ-irradiation than lymphocytes? (found in: Publications)
- Minimal Sizes of Deletions Detected by Comperative Genomic Hybridization (found in: Publications)
- Use of automated imaging and analysis technology for the detection of aneuploidy in human sperm (found in: Publications)
- Human ESCs predisposition to karyotypic instability: Is a matterof culture adaptation or differential vulnerability among hESC linesdue to inherent properties? (found in: Publications)
- Automation and validation of micronucleus detection in the 3D EpiDerm™human reconstructed skin assay and correlation with 2D dose responses. (found in: Publications)
- Ki67 index, HER2 status, and prognosis of patients with luminal Bbreast cancer. (found in: Publications)
- Creation of monosomic derivatives of human cultured cell lines (found in: Publications)
- A rapid, semi-automated method for scoring micronuclei in mononucleatedmouse lymphoma cells. (found in: Publications)
- Validation of automatic scanning of microscope slides in recoveringrare cellular events: application for detection of fetal cells inmaternal blood. (found in: Publications)
- Validation of a new classifier for the automated analysis of thehuman epidermal growth factor receptor 2 (HER2) gene amplificationin breast cancer specimens. (found in: Publications)
- INTERLABORATORY COMPARISON OF DICENTRIC CHROMOSOME ASSAY USING ELECTRONICALLYTRANSMITTED IMAGES. (found in: Publications)
- Delimiting the use of comparative genomic hybridization in human myeloid neoplastic disorders (found in: Publications)
- Mammalian Ino80 mediates double-strand break repair through its rolein DNA end strand resection. (found in: Publications)
- Evaluation of different biomarkers to predict individual radiosensitivityin an inter-laboratory comparison–lessons for future studies. (found in: Publications)
- Ionizing irradiation-induced radical stress stalls live meiotic chromosomemovements by altering the actin cytoskeleton. (found in: Publications)
- First description of the t(10;11)(q22;q23)/MLL-TET1 translocationin a T-cell lymphoblastic lymphoma, with subsequent lineage switchto acute myelomonocytic myeloid leukemia. (found in: Publications)
- Positive response to neoadjuvant cyclophosphamide and doxorubicinin topoisomerase II nonamplified/HER2/neu negative/polysomy 17 absentbreast cancer patients. (found in: Publications)
- Sesamol attenuates genotoxicity in bone marrow cells of whole-body γ-irradiated mice (found in: Publications)
- Mutations in SPRTN cause early onset hepatocellular carcinoma, genomicinstability and progeroid features. (found in: Publications)
- Multicolour FISH probe sets and their applications (found in: Publications)
- Automatic detection and genetic profiling of disseminated neuroblastoma cells. (found in: Publications)
- Automatic detection and genetic profiling of disseminated neuroblastoma cells (found in: Publications)
- The use of M-FISH and M-BAND to define chromosome abnormalities. (found in: Publications)
- Automated image analysis of micronuclei in binucleated human lymphocytes. (found in: Publications)
- FISH and tips: a large scale analysis of automated versus manual scoring for sperm aneuploidy detection (found in: Publications)
- Development of automated brightfield double In Situ hybridization (BDISH) application for HER2 gene and chromosome 17 centromere (CEN 17) for breast carcinomas and an assay performance comparison to manual dual color HER2 fluorescence In Situ hybridizatio (found in: Publications)
- Automated signal pattern evaluation of a bladder cancer specific multiprobe‐fish assay applying a user‐trainable workstation (found in: Publications)
- Genotoxicity of hydroquinone in A549 cells. (found in: Publications)
- Utilization of fluorescence in situ hybridization with cytokeratindiscriminators in TOP2A assessment of chemotherapy-treated patientswith breast cancer. (found in: Publications)
- Gene amplification in myeloid leukemias elucidated by fluorescence in situ hybridization. (found in: Publications)
- Automated analysis of fluorescence in situ hybridization on fixed, paraffin-embedded whole tissue sections in B-cell lymphoma. (found in: Publications)
- Validation of a fully automated COMET assay: 1.75 million singlecells measured over a 5 year period. (found in: Publications)
- Frequency of chromosomal aberrations in Prague mothers and theirnewborns. (found in: Publications)
- The impact of air pollution on the levels of micronuclei measured by automated image analysis. (found in: Publications)
- Alternative Lengthening of Telomeres: Recurrent Cytogenetic Aberrations and Chromosome Stability under Extreme Telomere Dysfunction. (found in: Publications)
- Persisting ring chromosomes detected by mFISH in lymphocytes of acancer patient-A case report. (found in: Publications)
- Automated Analysis of FISH-Stained HER2/neu Samples with Metafer. (found in: Publications)
- Recommendations, evaluation and validation of a semi-automated, fluorescent-basedscoring protocol for micronucleus testing in human cells. (found in: Publications)
- The radiation sensitivity of human chromosomes 2, 8, and 14 in peripheral blood lymphocytes of seven donors. (found in: Publications)
- Automated analysis of DNA damage in the high-throughput version ofthe comet assay. (found in: Publications)
- Digital morphology compared to the optical microscope: A validation study on reporting bone marrow aspirates. (found in: Publications)
- Comparison of results of the manual and automated scoring of micronucleus frequencies in (60)Co-irradiated peripheral blood lymphocytes for triage dosimetry. (found in: Publications)
- Chromosomal radiosensitivity of human immunodeficiency virus positive/negative cervical cancer patients in South Africa. (found in: Publications)
- Karyotype diversity suggests that Laonastes aenigmamus (Laotian rock rat) (Rodentia, Diatomyidae) is a multi-specific genus. (found in: Publications)
- Assessing fibrinogen extravasation into Alzheimer's disease brain using high-content screening of brain tissue microarrays. (found in: Publications)
- Comparison of Radiosensitivity of Human Chromosomes 1, 2 and 4 from One Healthy Donor (found in: Publications)
- Effect of low doses of estradiol and tamoxifen on breast cancer cell karyotypes. (found in: Publications)
- Sex chromosome diversity in Armenian toad grasshoppers (Orthoptera, Acridoidea, Pamphagidae). (found in: Publications)
- Karyotype alteration generates the neoplastic phenotypes of SV40-infected human and rodent cells. (found in: Publications)
- Karyotypic evolutions of cancer species in rats during the long latent periods after injection of nitrosourea. (found in: Publications)
- Effect of hyaluronic acids as chondroprotective in experimental model of osteoarthrosis. (found in: Publications)
- Telomere Length in Aged Mayak PA Nuclear Workers Chronically Exposed to Internal Alpha and External Gamma Radiation. (found in: Publications)
- Epigenetic regulation of lateralized fetal spinal gene expression underlies hemispheric asymmetries. (found in: Publications)
- Aneuploid CTC and CEC. (found in: Publications)
- Comprehensive in situ co-detection of aneuploid circulating endothelial and tumor cells (found in: Publications)
- Molecular atlas of the adult mouse brain. (found in: Publications)
- Radiation Biomarkers in Large Scale Human Health Effects Studies. (found in: Publications)
- Quantified postsurgical small cell size CTCs and EpCAM+ circulating tumor stem cells with cytogenetic abnormalities in hepatocellular carcinoma patients determine cancer relapse. (found in: Publications)
- DNA damage in leukocytes after internal ex-vivo irradiation of blood with the α-emitter Ra-223. (found in: Publications)
- Optimization of Immunofluorescent Detection of Bone Marrow Disseminated Tumor Cells. (found in: Publications)
- Erythropoietin Attenuates the Brain Edema Response after Experimental Traumatic Brain Injury. (found in: Publications)
- Characterization of Camptothecin-induced Genomic Changes in the Camptothecin-resistant T-ALL-derived Cell Line CPT-K5. (found in: Publications)
- Toxicological evaluation of nail polish waste discarded in the environment. (found in: Publications)
- ZW, XY, and yet ZW: Sex chromosome evolution in snakes even more complicated. (found in: Publications)
- Clarifying the Distinction Between Malignant Peripheral Nerve Sheath Tumor and Dedifferentiated Liposarcoma: A Critical Reappraisal of the Diagnostic Utility of MDM2 and H3K27me3 Status. (found in: Publications)
- Reprint of: A three-dimensional in vitro HepG2 cells liver spheroid model for genotoxicity studies. (found in: Publications)
- Intra-articular viscosupplementation of hyaluronic acids in an experimental osteoarthritis model. (found in: Publications)
- Establishing cytogenetic biodosimetry laboratory in Saudi Arabia and producing preliminary calibration curve of dicentric chromosomes as biomarker for medical dose estimation in response to radiation emergencies. (found in: Publications)
- Utility and performance of bacterial artificial chromosomes-on-beads assays in chromosome analysis of clinical prenatal samples, products of conception and blood samples. (found in: Publications)
- Optimization of prostate cancer cell detection using multiplex tyramide signal amplification. (found in: Publications)
- Biological Dosimetry Network in Africa: Establishment of a Dose-Response Curve Using Telomere and Centromere Staining. (found in: Publications)
- Machine-assisted interpretation of auramine stains substantially increases through-put and sensitivity of microscopic tuberculosis diagnosis. (found in: Publications)
- Classification of fluorescent R-Band metaphase chromosomes using a convolutional neural network is precise and fast in generating karyograms of hematologic neoplastic cells (found in: Publications)
- Efficient generation of human induced pluripotent stem cells from urine samples of patients with Fragile X syndrome (found in: Publications)