At the 2020 AACC Annual Scientific Meeting, you will have an unparalleled opportunity to connect with global leaders in laboratory medicine, and to discover cutting edge technology and vital research in the field.
Innovative Solutions for Automated Imaging
Since 1986 MetaSystems has been designing and manufacturing systems for computerized automated microscopic imaging. From the very beginning, the close relationship to the end user has been an essential part of the MetaSystems philosophy. The following three decades have revealed that this was a successful strategy; from humble beginnings, MetaSystems has grown into a leading solution provider which still remains connected to its strong roots.
MetaSystems’ latest innovation, Neon, is a dynamic, modern imaging platform which reliably manages cases, images, and results from single workstation environments to large multi-user, multi-site installations. The Neon imaging platform ensures that all relevant information is accessible whenever needed.
Maybe you can find a solution to your imaging automation problem here on this web site. We recommend starting your journey on the application pages, if you are not familiar with our product portfolio. In case you are, it may be easier to go directly to the page for the product you actually look for. Should you feel lost, please feel free to contact us or the MetaSystems partner in your country.
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Toxicology Studies with the Comet Assay and the in-vivo Micronucleus Assay
The genotoxic potential of azidothymidine [...], chosen as a model compound for nucleotide analogs, was comprehensively assessed in vivo for gene mutation, clastogenicity, and DNA breakage endpoints. [...] For the comet assay, liver and stomach were sampled. [...] Coded slides were analyzed by Metafer/Relosys4. A total of 150 comets per slide were measured. [...] For the micronucleus assay in bone marrow, the test methodology was in accordance with requirements of the OECD Guideline 474 [...]. A total of 4000 polychromatic erythrocytes (PCEs) per animal were evaluated for the occurrence of micronuclei and the relative proportion of PCE in relation to normochromatic erythrocytes (NCEs). Blinded slides were analyzed using the Metafer /Relosys 4. Statistical evaluation was performed for the frequency of micronucleated (MN)-PCE. [...] In the comet assay as well as the micronucleus test, AZT caused a considerable dose-dependent increase in DNA damage in all tissues evaluated and was highly cytotoxic to bone marrow and peripheral blood cells. These data are well in line with published results.
Are You Looking for Probes?
MetaSystems Probes now has its own website. If you are looking for MetaSystems XCyting DNA Probes, please visit the MetaSystems Probes website.
Website also available in Spanish
MetaSystems is pleased to announce that our website is now available in Spanish. With this change and the previously launched Portuguese language version, our customers and all interested parties from Latin America and Spain will be able to read information in their local language.
Publication: Machine-assisted interpretation of auramine stains
Of all bacterial infectious diseases, infection by Mycobacterium tuberculosis poses one of the highest morbidity and mortality burdens on humans throughout the world. [...] Here we validate a scanning and analysis system that combines fully-automated microscopy with deep-learning based image analysis.