The 12th European Cytogenomics Conference focuses on presentations about the rapid advances in the interlinked fields of cell and molecular biology, genomics and cytogenetics. The choice of topics and speakers, inspired by collaborative work between disciplines, includes a mixture of talks on technological advances in the field, and talks exploring new concepts in cytogenomics of humans, of non-human animals, and of plants.
Innovative Solutions for Automated Imaging
Since 1986 MetaSystems has been designing and manufacturing systems for computerized automated microscopic imaging. From the very beginning, the close relationship to the end user has been an essential part of the MetaSystems philosophy. The following three decades have revealed that this was a successful strategy; from humble beginnings, MetaSystems has grown into a leading solution provider which still remains connected to its strong roots.
MetaSystems’ latest innovation, Neon, is a dynamic, modern imaging platform which reliably manages cases, images, and results from single workstation environments to large multi-user, multi-site installations. The Neon imaging platform ensures that all relevant information is accessible whenever needed.
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Slide Imaging and Image Analysis for Diatom Morphometrics
Light microscopy analysis of diatom frustules is widely used in basic and applied research [...]. For image acquisition, we use a Metafer slide scanning system [...]. In position list
mode, a list of user-defined positions, spread arbitrarily over the slide, can be imaged. [...] The vertical position of objects can be determined by automatic creation of a focus map, i.e., based on interpolation between reference points, or by autofocusing at each position captured, or using a combination of both. [...] Our two-cycle microscopy and image analysis procedure starts with a low-resolution area scan [...]. The overlapping low-resolution images are stitched together to a virtual slide using the VSlide software [...]. For locating and selecting valves of interest, the low-resolution images [...] are processed by SHERPA. [...] We use the VSViewer software to import the position list provided by SHERPA [...] into the virtual slide [...]. The annotation function of the viewer enables to manually add positions of interest if some objects deemed relevant were missed by SHERPA [...]. This allows for combining (semi-)automated and manual selection of valves of interest. [...] The annotated virtual slide from step 5 contains the (X, Y) position data required for selectively imaging the valves of interest. [...]. Extending the size range reported for F. kerguelensis (quite substantially, by nearly 45% in the case of apical length) nicely illustrates the advantages of a (semi-)automated approach formicroscopic morphometry of diatom valves, primarily that it makes documenting and measuring large numbers of specimens feasible with moderate effort.
Are You Looking for Probes?
MetaSystems Probes now has its own website. If you are looking for MetaSystems XCyting DNA Probes, please visit the MetaSystems Probes website.
Workshop on Automated Cytogenetics in Mexico
Together with our partner Carl Zeiss de México S.A. de C.V., MetaSystems conducted a workshop addressing the automation of lab environments in cytogenetics, hematology, pathology, biodosimetry and other fields of work.
Workshop on Automated Genetic Toxicology at KIT, Daejeong, Korea
The Korea Institute of Toxicology (KIT) is a government-funded research institute to evaluate the safety of medicine, bio-related products and chemicals such as agricultural pesticides, food additives and cosmetics, environmental toxicity and ecotoxicity. As a leading provider of non-clinical toxicology studies, KIT serves as a core infrastructure in the biotechnology industry. In May 2019, Dr. Seong-Hoon Park from KIT organized the first KIT Workshop for Automated Genetic Toxicology Testing. On this event, which was kindly supported by Mirax Corporation, local and overseas speakers summarized current proceedings in the automation of genetic toxicology test analysis.