The ERRS meeting series belongs to a tradition of European conferences on radiation research initiated already in 1953. This year’s meeting is jointly organized by the Swedish Radiobiological Society and Lund University. Due to the Covid-19 pandemic, this event will be organized as a virtual conference.
Innovative Solutions for Automated Imaging
Since 1986 MetaSystems has been designing and manufacturing systems for computerized automated microscopic imaging. From the very beginning, the close relationship to the end user has been an essential part of the MetaSystems philosophy. The following three decades have revealed that this was a successful strategy; from humble beginnings, MetaSystems has grown into a leading solution provider which still remains connected to its strong roots.
MetaSystems’ latest innovation, Neon, is a dynamic, modern imaging platform which reliably manages cases, images, and results from single workstation environments to large multi-user, multi-site installations. The Neon imaging platform ensures that all relevant information is accessible whenever needed.
Maybe you can find a solution to your imaging automation problem here on this web site. We recommend starting your journey on the application pages, if you are not familiar with our product portfolio. In case you are, it may be easier to go directly to the page for the product you actually look for. Should you feel lost, please feel free to contact us or the MetaSystems partner in your country.
We believe in communication being the first step towards innovative solutions!
Toxicology Studies with the Comet Assay and the in-vivo Micronucleus Assay
The genotoxic potential of azidothymidine [...], chosen as a model compound for nucleotide analogs, was comprehensively assessed in vivo for gene mutation, clastogenicity, and DNA breakage endpoints. [...] For the comet assay, liver and stomach were sampled. [...] Coded slides were analyzed by Metafer/Relosys4. A total of 150 comets per slide were measured. [...] For the micronucleus assay in bone marrow, the test methodology was in accordance with requirements of the OECD Guideline 474 [...]. A total of 4000 polychromatic erythrocytes (PCEs) per animal were evaluated for the occurrence of micronuclei and the relative proportion of PCE in relation to normochromatic erythrocytes (NCEs). Blinded slides were analyzed using the Metafer /Relosys 4. Statistical evaluation was performed for the frequency of micronucleated (MN)-PCE. [...] In the comet assay as well as the micronucleus test, AZT caused a considerable dose-dependent increase in DNA damage in all tissues evaluated and was highly cytotoxic to bone marrow and peripheral blood cells. These data are well in line with published results.
Are You Looking for Probes?
MetaSystems Probes now has its own website. If you are looking for MetaSystems XCyting DNA Probes, please visit the MetaSystems Probes website.
Newly discovered security leak Ripple20 and MetaSystems devices
Lately it was discovered that many networked devices are vulnerable to remote attacks through 19 vulnerabilities. The flaws, collectively known as Ripple20, affect the TCP/IP stack. Unfortunately, also PC hardware used in combination with MetaSystems devices may be affected, and problems may arise if the network settings are not configured correctly or the workstation is connected directly to the internet. We therefore encourage our customers to update their system(s) to the latest firmware versions provided by the manufacturer.
Development of High Precision SARS-COV-2 (RNA) FISH Probes
The outbreak of the SARS-CoV-2 virus has led to global efforts to understand the mechanisms of the virus-induced Covid-19 disease and to seek to find effective countermeasures. In this context, our daughter company MetaSystems Italy joined forces with RNA-FISH specialist PixelBiotech for development of highly sensitive and precise SARS-Covid-2 probes.
Download the leaflet with details about the new technology here.