Metafer
The versatile Metafer slide scanning software offers automation for various imaging applications in life sciences microscopy.
Metafer is a software platform designed to manage standard microscopes and related hardware. It facilitates the scanning of light microscope slides, the acquisition of digital images, the application of standard image processing techniques, and the measurement of general image features.
- Capture up to 800 slides seamlessly in a single session.
- Utilize various contrasting methods, including but not limited to brightfield, fluorescence, phase contrast, darkfield, and more.
- Effortlessly link and combine different imaging tasks, letting Metafer engage the objectives, and benefit from an automated immersion oil dispenser.
- Enable barcode reading for specimen identification and tracking, allowing Metafer to capture images from the frosted end of the specimen.
- Take advantage of a range of settings to establish automated focusing tailored to the specimen's specifics.
- Review all imaging results in a well-organized image gallery.
- Efficiently relocate identified objects on the microscope with a single mouse click.
- Customize workflows according to your preferences using a flexible classifier-based imaging approach.
- Expand your imaging network by integrating multiple workstations managed by Metafer and Ikaros.
Utilizing the Metafer software, imaging systems scan specimens of diverse sizes, employ various contrasting methods and magnifications, and identify, classify, and enumerate cells or other objects. Metafer's modularity and flexible architecture make it proficient in assisting users from various fields with their specific imaging tasks.
In contrast to complex analysis systems that can be unwieldy and challenging to navigate, Metafer's intelligent scanning offers a different experience: unhindered access to all data, a user-friendly display of results, and complete control over imaging parameters to ensure precise results according to your preferences. With Metafer, slide scanning becomes remarkably straightforward.
Given the variability of each microscopic sample, automated imaging demands flexibility. Metafer's distinctive concept provides an effective solution: user-trainable classifiers accurately establish imaging standards, and by selecting the relevant classifier, the integrated scanning system swiftly transitions to the next task.
MetaSystems solutions are adaptable to your expanding requirements. The modular software and supported hardware allow for increased automation as the workload grows. Additional accessories like the SlideFeeder x80, a barcode reader, and an automatic immersion oil dispenser can be seamlessly incorporated as needed.
Neon is a convenient interface for organizing case and image data. Users configure overview dashboards to summarize cases, processing statuses, and case statistics. Interfaces for data exchange with external databases can be adapted. The fields on case data sheets and reports are customizable to meet specific needs.
Neon serves as general data management software.
The flexible smart scanning facilitated by Metafer software suggests numerous options, each tailored to specific hardware accessories and software requirements, for various customizations. A variety of software license subsets and hardware options are at your disposal. Commonly, Metafer software-controlled integrated systems consist of one of four camera models and a motorized stage. A fully integrated system requires a motorized microscope. MetaSystems can incorporate the microscope into the installation, although the Metafer software can also be integrated with existing, compatible microscopes.
- Metafer (5.0MB)
Metafer, MetaSystems' scanning and imaging software, controls microscope and accessory hardware to acquire digital images, and to assist the operator in the detection, classification, and counting of cells of human or other origin and other objects in microscopic specimen.
- Case and Image Data Management (1.3MB)
Neon is a technology for the flexible and consistent management of image and case data. It is designed to collect data from a variety of sources and integrate them into an efficient and well-structured workflow. The technology integrated in all MetaSystems installations ensures that all relevant information is available wherever it is needed.
- CPs for Toxicology (644.5kB)
Many laboratories worldwide benefit from Metafer imaging automation in genetic toxicology. Standardization is key to genetic toxicology testing. The often very subtle effects can only be reliably detected if all aspects of the test, including the scoring, are performed based on standardized parameters.
- CP Metaphase Detection DNN (358.2kB)
The DNN-based metaphase detection can be added to any Metafer-based metaphase finder as a Customization Package. The approach typically yields metaphases of superior quality compared to those identified by traditional algorithms. The method has the potential to not only boost the overall count of detected metaphases but to also decrease the need for recording metaphases at high resolutions.
- CP Sperm Detection (551.7kB)
Sperm cell identification serves as a widely utilized forensic analytical technique in the examination of sexual offenses. MetaSystems has put together a workflow incorporating Deep Neural Networks (DNN) technology within the Metafer scanning software. This customization has the potential to speed up and simplify sperm detection in forensic examinations.
- CP Spot Counting (1.2MB)
The Customization Package Spot Counting workflow streamlines the management of FISH cases and bears the potential to lead to a notable reduction in processing time. At the heart of the workflow lies the essential RapidScore review process. This crucial step empowers experts to efficiently evaluate data, focusing precisely on areas of interest while identifying any potential anomalies.
- CPs for Biodosimetry (1.2MB)
The standardization of microscopy offers significant advantages by fostering uniformity and reliability across diverse research settings. It promotes resource sharing, collaborative research, and the development of universally accepted guidelines and regulations, ultimately advancing the field of radiation safety and public health on a global scale.
- CP Mycobacteria Detection (291.5kB)
With the support of our application specialists, users can set up a workflow that enables the automated acquisition of Auramine-stained slides. Users can implement a customized Deep Neural Network (DNN) to pre-qualify the found objects. You can also choose to set up a suggested grading of the detected Auramine-stained objects.
Also available in: - CP Extended Blood Cell Detection (403.8kB)
Whole Blood Cell (WBC) counting determines the relative distribution of leukocyte subtypes and is crucial for diagnosing infections, immune disorders, and hematological diseases. The Customization Package for Extended Blood Cell Detection enables you to use DNN-powered workflows for automated whole blood cell counting with your Metafer installation. The workflows integrate DNNs trained on expert-annotated data and are ready for implementation and validation in your lab.
Metafer 4.3 is classified as an in vitro diagnostic (IVD) medical device within the European Union in accordance with the In Vitro Diagnostics Regulation (EU) 2017/746. It carries the CE label unless otherwise indicated and must be used within the scope of its intended purpose.
Metafer is utilized in numerous countries worldwide. However, its use for clinical diagnostics depends on the regulatory requirements of each respective country or region.
Please note that the hardware components depicted are not part of the Metafer IVD product and are supplied by third-party manufacturers.