On February 04 is World Cancer Day, and we would like to use this day as an opportunity to present our solutions for automated microscope-based imaging.

The MetaSystems team is looking forward to 2023 with great enthusiasm.

Another exciting year is slowly coming to an end.

After a year full of challenges and changes, there is no better time to thank our customers, partners, and friends for their loyalty and trust. We appreciate your understanding for any delays due to the exceptional situation and look forward to supporting you with our products and services in 2023.

It was a great pleasure to meet our distributors from around the world for the 20th time.

October is Breast Cancer Awareness Month, and we have highlighted the automation of HER2 FISH microscopy.

Read how our collaboration with MLL Münchner Leukämielabor on AI-based chromosome analysis is reducing their turnaround time.

The case and image management software called Neon is an integrated part of Ikaros, the karyotyping software, and Metafer, the slide scanning software. We have highlighted some of the unique features of Neon.

Following a radiation accident, a rapid assessment of the dose received by victims is critical. Biological dosimetry allows a range of tests, many of which are based on microscopy, to provide a retrospective estimate of the dose received.

Our advanced deep learning algorithms in Ikaros simplify the entire preparation process for karyotype analysis, from chromosome separation to classification. Read our article on AI-driven Intelligent Karyotyping with Ikaros.

On May 26, 2022, In Vitro Diagnostics Regulation (IVDR; Regulation (EU) 2017|746) becomes mandatory and replaces the In Vitro Diagnostics Directive (IVDD; Directive 98/79/EC). However, a progressive roll-out of the new IVDR was decided for existing products.

We are following the current events in Ukraine with great concern. We have therefore decided to suspend our deliveries to Russia until further notice.

After becoming aware of the security vulnerability in the Java library Log4j, we immediately investigated the matter. After a careful review, we can inform you that MetaSystems’ software is not affected by the Log4j security gap.

35 Years of MetaSystems
Today and Tomorrow

35 Years of MetaSystems
Year 35: 2020

35 Years of MetaSystems
Year 34: 2019

35 Years of MetaSystems
Year 33: 2018

35 Years of MetaSystems
Year 32: 2017

35 Years of MetaSystems
Year 31: 2016

35 Years of MetaSystems
Year 30: 2015

Automate and standardize forensic sperm detection with the help of artificial intelligence! Meet us at EAFS 2022 in Stockholm.

35 Years of MetaSystems
Year 29: 2014

35 Years of MetaSystems
Year 28: 2013

35 Years of MetaSystems
Year 27: 2012

35 Years of MetaSystems
Year 26: 2011

35 Years of MetaSystems
Year 25: 2010

35 Years of MetaSystems
Year 24: 2009

35 Years of MetaSystems
Year 23: 2008

35 Years of MetaSystems
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35 Years of MetaSystems
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35 Years of MetaSystems
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35 Years of MetaSystems
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35 Years of MetaSystems
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35 Years of MetaSystems
Year 17: 2002

35 Years of MetaSystems
Year 16: 2001

35 Years of MetaSystems
Year 15: 2000

The congress is intended for laboratory professionals from biomedical laboratory scientists, chemists, and physicians to microbiologists, geneticists, etc., and also product importers and manufacturers in the field.

35 Years of MetaSystems
Year 14: 1999

35 Years of MetaSystems
Year 13: 1998

35 Years of MetaSystems
Year 12: 1997

35 Years of MetaSystems
Year 11: 1996

35 Years of MetaSystems
Year 10: 1995

35 Years of MetaSystems
Year 9: 1994

35 Years of MetaSystems
Year 8: 1993

35 Years of MetaSystems
Year 7: 1992

35 Years of MetaSystems
Year 6: 1991

35 Years of MetaSystems
Year 5: 1990

35 Years of MetaSystems
Year 4: 1989

35 Years of MetaSystems
Year 3: 1988

35 Years of MetaSystems
Year 2: 1987

35 Years of MetaSystems
Year 1: 1986

Thin and thick film evaluations are the gold standard of malaria diagnostic tests. MetaSystems, in collaboration with the University of Milano and the Ospedale Fatebenefratelli-Sacco, Milano, has developed a deep learning algorithm to improve the sensitivity and specificity of malaria microscopy-based evaluations.

Last Friday, 05/28/2021, we noticed a criminal attack on MetaSystems accounts. As a result, the attackers sent eMails that appeared to have been written and sent by MetaSystems employees. Please note that these mails were not sent by MetaSystems!

Artificial intelligence opens entirely new horizons for image analysis. In the latest versions of Ikaros, MetaSystems has implemented Deep Neural Network (DNN) based artificial intelligence that greatly facilitates the processing of metaphase images for karyotyping. MetaSystems is proud to announce that our innovative DNN-based technology has now received a patent entitled ‘Methods for Automated Chromosome Analysis’” (U.S. patent no. 10,991,098).

Theresia Bauer, Minister of Science, Research and the Arts for the State of Baden-Württemberg, Germany visited MetaSystems to get an impression of the work of this 'Hidden Champion' in life sciences sector.

Researchers led by dermatologist Raffaele Gianotti of the University of Milan and pathologist Prof. Massimo Barberis, director of the Molecular Pathology Unit at Institute of European Oncology in Milan, report evidence of early SARS-CoV-2 infection in an Italian patient.

Wibu-Systems has disclosed several vulnerabilities in their software CodeMeter Runtime. This software is also used by our products for license management. Wibu-Systems has released an updated version of the CodeMeter Runtime which addresses these issues. We strongly advise you to install the new version 7.10b or higher.

An unusual year is now almost behind us. We would like to thank all our customers, partners and friends for staying with us through these difficult times.

MetaSystems is pleased to announce that our website is now available in Spanish. With this change and the previously launched Portuguese language version, our customers and all interested parties from Latin America and Spain will be able to read information in their local language.

Of all bacterial infectious diseases, infection by Mycobacterium tuberculosis poses one of the highest morbidity and mortality burdens on humans throughout the world. [...] Here we validate a scanning and analysis system that combines fully-automated microscopy with deep-learning based image analysis.

The International Atomic Energy Agency (IAEA) is setting up a reference laboratory for biodosimetry/radiobiology in Seibersdorf/Austria. MetaSystems and its long-standing partner Carl Zeiss Germany have donated a fully equipped, automated evaluation platform for the laboratory in Seibersdorf.

Lately it was discovered that many networked devices are vulnerable to remote attacks through 19 vulnerabilities. The flaws, collectively known as Ripple20, affect the TCP/IP stack. Unfortunately, also PC hardware used in combination with MetaSystems devices may be affected, and problems may arise if the network settings are not configured correctly or the workstation is connected directly to the internet. We therefore encourage our customers to update their system(s) to the latest firmware versions provided by the manufacturer.

The outbreak of the SARS-CoV-2 virus has led to global efforts to understand the mechanisms of the virus-induced Covid-19 disease and to seek to find effective countermeasures. In this context, our daughter company MetaSystems Italy joined forces with RNA-FISH specialist PixelBiotech for development of highly sensitive and precise SARS-Covid-2 probes.

Download the leaflet with details about the new technology here.

MetaSystems is pleased to announce that our website is also now available in Brazilian Portuguese. With this change, our customers and all interested parties from one of our largest markets in Latin America will be able to read information in their local language.

The worldwide outbreak of the Sars-CoV-2 virus has led to severe limitations. In many places lab employees are confined to their homes. Working remotely from home may be the only way to assure a continued high level of diagnostic services.

Against the background of the worldwide appearance of the Corona virus (Sars CoV-2), the most important task for everyone at present is to contribute to slowing down its speed of propagation by adapting their behavior. Nevertheless, we are striving to maintain our services as far as possible and provide our customers and partners with the usual good service.

With this advance notice, MetaSystems proudly announces the launch of its first product utilizing Deep Neural Networks (DNN) for image analysis. In one of the next versions of the outstanding karyotyping system Ikaros, artificial intelligence (AI) will be used to assign chromosomes automatically to their respective classes.

About 100 guests from 36 countries met on the XVIII. MetaSystems Distributor Meeting (DM) in November to exchange experiences and to get to know new trends and developments at MetaSystems.

Neon, the outstanding MetaSystems case and image management system, offers many tools and helpful gadgets to streamline routine workflows, for example in cytogenetics labs. The second MetaSystems User Day, addressed to MetaSystems clients from Germany, Austria, and Switzerland, provided in different workshops knowledge helping to unleash the full power of the system.

The Congress 'Genetics of XXI Century' in Moscow, Russia (May 2019) has been one of the most important events for the professional international community of geneticists. Our partner company in Russia OOO MetaSystems considered it a good occasion to present the new camera CoolCube 4 connected to a state-of-the-art Neon system to the public.

N.N.Burdenko National Scientific and Practical Center for Neurosurgery is one of the first MetaSystems’ customers in Russia who implemented FISH on tissues into their daily practice ( in the late 90ies). Our partner in Russia, OOO MetaSystems therefore provides comprehensive support of all initiatives shown by the head of pathology lab and its staff.

Together with our partner Carl Zeiss de México S.A. de C.V., MetaSystems conducted a workshop addressing the automation of lab environments in cytogenetics, hematology, pathology, biodosimetry and other fields of work.

The Korea Institute of Toxicology (KIT) is a government-funded research institute to evaluate the safety of medicine, bio-related products and chemicals such as agricultural pesticides, food additives and cosmetics, environmental toxicity and ecotoxicity. As a leading provider of non-clinical toxicology studies, KIT serves as a core infrastructure in the biotechnology industry. In May 2019, Dr. Seong-Hoon Park from KIT organized the first KIT Workshop for Automated Genetic Toxicology Testing. On this event, which was kindly supported by Mirax Corporation, local and overseas speakers summarized current proceedings in the automation of genetic toxicology test analysis.

MetaSystems, a worldwide leader in microscopic imaging innovation, presented proof of concept results for Deep Learning - based pathogen classification on Gram stain slides.

The meeting of the German Society of Human Genetics (gfh) was held in Weimar, Germany this week and of course the attendees had the opportunity to visit the joined booth of MetaSystems and MetaSystems Probes. Main topics of the exhibition have been the latest advancements of the Neon case and imaging platform and RapidHyb, the revolutionary fast hybridization times of MetaSystems Probes' FISH probes.

An "International Workshop on Genomic Instability: Basic and Applied Aspects" was jointly organized by Environmental Mutagen Society of India (EMSI) and School of Bio-sciences and Technology, Vellore Institute of Technology under the guidance of Prof. Wilner Martinez-Lopez (Biological Research Institute “Cemente Estable”-Uruguay, IIBCE) and Prof. Radha Saraswathy (School of Bio-sciences and Technology, VIT).

As of late, freshmen studying for the Medical Degree in Linz, Austria are trained in the use of the Ikaros karyotyping system.

MetaSystems proudly announces the opening of our first subsidiary in the Southern hemisphere. The new office is located in Buenos Aires, Argentina and bears the name MetaSystems Latinoamérica SAS (MetaSystems LatAm). The foundation has been the response to the growing demand on technical knowledge and 'know how' experienced in the last years all over the Latin American territories. MetaSystems LatAm takes care for the organization of sales, support, and customer relation activities in all countries in Latin America. It will manage distributor companies and contacts in the region, and it will facilitate communication between end-users, distributors and headquarters in Germany.

Carl Zeiss Microscopy, longtime partner of MetaSystems,  recently published a technical note entitled "Light Microscopy in Clinical Routine Activities. An Overview of ZEISS Axio Imager and Metafer from MetaSystems". The brochure summarizes the history of Metafer and the fruitful partnership with Carl Zeiss and combines both with background knowledge on the many applications Metafer is used for.

A “Hands-on Workshop on FISH and its application in Pathology and Clinical Medicine” was organized by MetaSystems and Department of Pathology, Himalayan Institute of Medical Sciences (HIMS) to demonstrate the applications of FISH in hematological malignancies and solid tumors.

The yearly MetaSystems Distributor Meeting (DM), brought into life in 2002 as a platform to gather all international partners of MetaSystems and other members of the global MetaSystems family, just ended last week. The DM is being organized in turns by MetaSystems Headquarters, MetaSystems USA (MGI), and MetaSystems Asia. Since MGI is celebrating its 25th anniversary in 2018 they decided to choose a special location: Nassau, The Bahamas!

As the first abroad office of MetaSystems, MetaSystems Group, Inc. (MGI) will turn 25 years in 2019. Therefore the company, being the official organizer of the 2018 MetaSystems Distributor Meeting (DM) took advantage of this fact and Dr. Uli Klingbeil, founder of MGI, presented the history of the company on this event. As an acknowledgement of all staff members who helped turning MGI into the thriving enterprise it today is, the company celebrated its birthday on the white sands of the Bahamas, next to Nassau on New Providence Island.

The first MetaSystems User Day took place in Altlussheim, Germany in the last week of September 2018. Approximately 25 guests took the opportunity to learn about the benefits of Neon, RapidScore, and the latest MetaSystems FISH probes.

MetaSystems attended the 2018 International Congress of Genetics being held in Foz do Iguacu, Brazil. The conference is known as one of the most important gatherings in the field of genetics in Latin America. Accordingly, the MetaSystems booth traffic was very busy. People from many Latin American countries took the opportunity to learn more about the latest MetaSystems products including Neon, Metafer, and the latest probes.

MetaSystems proudly announces the launch of the new ultra-high resolution cameras CoolCube4 and CoolCube4 TEC which are available for MetaSystems imaging devices from now on. The new CoolCube4 camera series encompasses 4 models of 1.1" CMOS cameras with resolutions of 4,096 x 3,000 pixels. Users can choose between two monochrome and two color models without active cooling (CoolCube4) or thermo-electrically cooled (CoolCube4 TEC).

At the 28th ECCMID conference in Madrid (April 21-24), MetaSystems GmbH introduces the first assay of its DMI product line. The Bacteremia DMI kit allows identification of the 12 most relevant bacteremia-causing pathogens directly from positive blood cultures in just 35 minutes.

The 3rd International and 15th Iranian Genetic Congress in Tehran was held last week. Our partner VITCO / Vira Idea Trade Co. represented MetaSystems and MetaSystems Probes on the industrial exhibition.

MetaSystems and MetaSystems Probes performed a workshop with exercises in classical FISH hybridization, short time hybridization, RapidScore analysis with Metafer and imaging with Isis. The workshop was done in two groups from Feb. 02 to Feb. 05 in Dubai. UAE.

Since 16 years, the MetaSystems Distributor Meeting (DM) is the annual get-together for all members of the global MetaSystems family. Staff of all MetaSystems offices, of partner companies, and of local sales organizations met in November 2017 to discuss the latest MetaSystems developments and achievements. The 2017 DM was held in the light of two major events, namely, (a) the launch of the first release version of Neon, the image and case database for all MetaSystems products and (b) the latest diversification on the field of microbiology applications.

MetaSystems is proud to be committed to sustainable business and to the safeguarding of social and ecological standards. As a result of this philosophy, MetaSystems recently was awarded again the seal of approval 2018 "Commitment to Sustainability" by the certification body of the German institute for Sustainability and Economy in accordance with di-no. - Procedural Regulation D-17/400780, and documented in Analysis Report No. 4017 3201 and relevant Audit Report No. 4017 3201. MetaSystems will take this award as inducement to continue with our sustainable business practices and socially responsible activities.

Biological dosimetry (biodosimetry) is an imminent part of the countermeasures in the aftermath of radiation accidents. Based on the quantification of markers in the blood of affected victims (e.g., dicentric chromosomes, micronuclei, or translocations), the method allows for a precise and retrospective estimation of the dose the persons have received. The National Radiation Emergency Medical Center (NREMC) in the Korea Institute of Radiological & Medical Sciences (KIRAMS) recently hosted a MetaSystems workshop on the implementation of Metafer for biodosimetry imaging automation. The workshop has been supported by our Korean partner Mirax Corporation.

Our Partner in Japan, Carl Zeiss Microscopy Co., Ltd (カールツァイスマイクロスコピー株式会社), recently published a Metafer brochure in Japanese language.

MetaSystems held its second workshop in the Middle East this year between the 18th and 21st of February in Dubai, UAE. This time, in addition to a system demonstration, a probes workshop was also included. Over the course of two different workshops (one on the 18th/19th, one on the 20th/21st), 29 participants from 5 countries experienced the ease and quality of MetaSystems FISH probes, software, and hardware. Participants came from Pakistan, Iran, the UAE, Oman, and Lebanon.

For the first time this year, MedLab in Dubai, the world’s largest laboratory exhibition and congress, took place separately from the ArabHealth. Being a leader in microscope based imaging, MetaSystems decided to attend this event in 2017 and to take advantage of direct contacts to regional sales representatives, partner companies, and customers. All companies of the MetaSystems family, namely MetaSystems, MetaSystems Probes, and for the first time MetaSystems Indigo were present at the booth and provided latest news on their respective products and innovations.

Our US team was recently awarded ISO 13485 certification! Here are some pictures taken during the celebration. At MetaSystems, we strive after continuously improving the quality of our service and products!

The XV. MetaSystems Distributor Meeting (DM) has taken place in Hong Kong in from December 06. - 08. Since 2002, MetaSystems and MetaSystems Probes invite distributors and partners from all countries to learn about latest product and application developments, to exchange their market experience with others, and to deepen the friendship of all members of the MetaSystems family.

MetaSystems is very proud to announce that it has now been active and independent for 3 full decades. Back in the late nineteen-eighties, MetaSystems' began its humble but promising journey. From the seed of just one brilliant idea grew an incomparable company. Thirty years later, the company is inseparably associated with the most reliable and top-quality microscope based imaging solutions.

MetaSystems presented a fully equipped Metafer system with SlideFeeder x80 on two scientific congresses in Latin America (October 2016).

Neon represents the next generation of MetaSystems' imaging systems for microscopy. At the 10th European Chromosome Conference held in Strasbourg (France), 4. - 7. July 2015, an early version of Neon has been shown to the public for the first time. Read more about the new system on the Neon product page.