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Innovative Solutions for Automated Imaging

Since 1986 MetaSystems has been designing and manufacturing systems for computerized automated microscopic imaging. From the very beginning, the close relationship to the end user has been an essential part of the MetaSystems philosophy. The following three decades have revealed that this was a successful strategy; from humble beginnings, MetaSystems has grown into a leading solution provider which still remains connected to its strong roots.

MetaSystems’ latest innovation, Neon, is a dynamic, modern imaging platform which reliably manages cases, images, and results from single workstation environments to large multi-user, multi-site installations. The Neon imaging platform ensures that all relevant information is accessible whenever needed.

Maybe you can find a solution to your imaging automation problem here on this web site. We recommend starting your journey on the application pages, if you are not familiar with our product portfolio. In case you are, it may be easier to go directly to the page for the product you actually look for. Should you feel lost, please feel free to contact us or the MetaSystems partner in your country.

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Toxicology Studies with the Comet Assay and the in-vivo Micronucleus Assay

The genotoxic potential of azidothymidine [...], chosen as a model compound for nucleotide analogs, was comprehensively assessed in vivo for gene mutation, clastogenicity, and DNA breakage endpoints. [...] For the comet assay, liver and stomach were sampled. [...] Coded slides were analyzed by Metafer/Relosys4. A total of 150 comets per slide were measured. [...] For the micronucleus assay in bone marrow, the test methodology was in accordance with requirements of the OECD Guideline 474 [...]. A total of 4000 polychromatic erythrocytes (PCEs) per animal were evaluated for the occurrence of micronuclei and the relative proportion of PCE in relation to normochromatic erythrocytes (NCEs). Blinded slides were analyzed using the Metafer /Relosys 4. Statistical evaluation was performed for the frequency of micronucleated (MN)-PCE. [...] In the comet assay as well as the micronucleus test, AZT caused a considerable dose-dependent increase in DNA damage in all tissues evaluated and was highly cytotoxic to bone marrow and peripheral blood cells. These data are well in line with published results.

Cited From: Toxicol Sci (2013) Read more...
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MetaSystems Probes now has its own website. If you are looking for MetaSystems XCyting DNA Probes, please visit the MetaSystems Probes website.

Next Event

20th Annual Meeting of Chinese Society of Clinical Oncology

Upcoming Event in China from Sep 26 to Sep 30, 2017

Link to Event Website

In the global fight against cancer, people at every corner of the world are trying their best to make contributions, and China is no exception. As a non-government association, the Chinese Society of Clinical Oncology (CSCO) holds its academic meeting annually providing a face-to-face contact to professionals from all over the world. This is a remarkable time when we can all make a difference. We sincerely invite you to come and join us.

Our customer and partner Cytointelligen (www.cytointelligen.com) will exhibit on this conference and also demonstrate the Metafer-based solution for automated detection of circulating tumor cells.

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Latest News

ECA 2017 in Florence

The European Cytogeneticists Association (E.C.A) yearly meeting, the 11th European Cytogenetics Conference took place in Florence, Italy and MetaSystems was proud to be sponsor and exhibitor of this event. Visitors to the MetaSystems booth had the opportunity to see the current pre-release edition of Neon, probably the last one before the official product launch. Of course also MetaSystems Probes took the opportunity to provide cytogeneticists and other passersby to show and explain the newest probe kits and product lines. The German MetaSystems team has been actively supported by the colleagues from MetaSystems s.r.l. in Milan.

ECA 2017 in Florence

MetaSystems Indigo Exhibition on ASM 2017 in New Orleans

The growing success of microbiology related applications within the MetaSystems product portfolio led to the launch of MetaSystems Indigo, the new MetaSystems brand which unites all microbiology products under the same roof. The ASM 2017 show in New Orleans, LA (USA) has been the venue of the second MetaSystems Indigo presentation after the ECCMID 2017 in Europe.

MetaSystems Indigo Exhibition on ASM 2017 in New Orleans
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