The Cancer Genomics Consortium annual summer meeting is a unique forum for education and discussion of best practices in laboratory genomics. The CGC is committed to advancing clinical diagnostics through the use of genomic technologies (microarray, massively parallel sequencing, etc.) and improving the data processing that accompanies these technologies.
Innovative Solutions for Automated Imaging
Since 1986 MetaSystems has been designing and manufacturing systems for computerized automated microscopic imaging. From the very beginning, the close relationship to the end user has been an essential part of the MetaSystems philosophy. The following three decades have revealed that this was a successful strategy; from humble beginnings, MetaSystems has grown into a leading solution provider which still remains connected to its strong roots.
MetaSystems’ latest innovation, Neon, is a dynamic, modern imaging platform which reliably manages cases, images, and results from single workstation environments to large multi-user, multi-site installations. The Neon imaging platform ensures that all relevant information is accessible whenever needed.
Maybe you can find a solution to your imaging automation problem here on this web site. We recommend starting your journey on the application pages, if you are not familiar with our product portfolio. In case you are, it may be easier to go directly to the page for the product you actually look for. Should you feel lost, please feel free to contact us or the MetaSystems partner in your country.
We believe in communication being the first step towards innovative solutions!
Toxicology Studies with the Comet Assay and the in-vivo Micronucleus Assay
The genotoxic potential of azidothymidine [...], chosen as a model compound for nucleotide analogs, was comprehensively assessed in vivo for gene mutation, clastogenicity, and DNA breakage endpoints. [...] For the comet assay, liver and stomach were sampled. [...] Coded slides were analyzed by Metafer/Relosys4. A total of 150 comets per slide were measured. [...] For the micronucleus assay in bone marrow, the test methodology was in accordance with requirements of the OECD Guideline 474 [...]. A total of 4000 polychromatic erythrocytes (PCEs) per animal were evaluated for the occurrence of micronuclei and the relative proportion of PCE in relation to normochromatic erythrocytes (NCEs). Blinded slides were analyzed using the Metafer /Relosys 4. Statistical evaluation was performed for the frequency of micronucleated (MN)-PCE. [...] In the comet assay as well as the micronucleus test, AZT caused a considerable dose-dependent increase in DNA damage in all tissues evaluated and was highly cytotoxic to bone marrow and peripheral blood cells. These data are well in line with published results.
Are You Looking for Probes?
MetaSystems Probes now has its own website. If you are looking for MetaSystems XCyting DNA Probes, please visit the MetaSystems Probes website.
ECA 2017 in Florence
The European Cytogeneticists Association (E.C.A) yearly meeting, the 11th European Cytogenetics Conference took place in Florence, Italy and MetaSystems was proud to be sponsor and exhibitor of this event. Visitors to the MetaSystems booth had the opportunity to see the current pre-release edition of Neon, probably the last one before the official product launch. Of course also MetaSystems Probes took the opportunity to provide cytogeneticists and other passersby to show and explain the newest probe kits and product lines. The German MetaSystems team has been actively supported by the colleagues from MetaSystems s.r.l. in Milan.
MetaSystems Indigo Exhibition on ASM 2017 in New Orleans
The growing success of microbiology related applications within the MetaSystems product portfolio led to the launch of MetaSystems Indigo, the new MetaSystems brand which unites all microbiology products under the same roof. The ASM 2017 show in New Orleans, LA (USA) has been the venue of the second MetaSystems Indigo presentation after the ECCMID 2017 in Europe.