Radiation Biodosimetry Workshop at KIRAMS, Seoul, Korea

Sep 28, 2017

Biological dosimetry (biodosimetry) is an imminent part of the countermeasures in the aftermath of radiation accidents. Based on the quantification of markers in the blood of affected victims (e.g., dicentric chromosomes, micronuclei, or translocations), the method allows for a precise and retrospective estimation of the dose the persons have received. The National Radiation Emergency Medical Center (NREMC) in the Korea Institute of Radiological & Medical Sciences (KIRAMS) recently hosted a MetaSystems workshop on the implementation of Metafer for biodosimetry imaging automation. The workshop has been supported by our Korean partner Mirax Corporation.

NREMC was constituted to prepare a countermeasure of medical preparedness and response involved in nuclear/radiological disaster in 2003 by the Korean "Act on Physical Protection and Radiological Emergency." NREMC runs three Metafer1 systems for automation of biodosimentry imaging and uses the chromosomal aberrations test, the micronucleus test, the FISH translocation assay and multicolor FISH to assess radiation induced DNA damage. On the workshop, strategies for Metafer1 based assays have been discussed and implemented.

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1 MetaSystems products are used in many countries worldwide. Depending on the regulations of the respective country or region, some products may not be used for clinical diagnostic use. In Europe MetaSystems products are CE labelled in-vitro diagnostics (IVD) devices. In the USA all MetaSystems products except the Ikaros karyotyping systems are intended to be used for research or inspection only.