MetaSystems is proud to present a high-performance solution to detecting SARS-CoV-2 RNA in cell and tissue samples, in partnership with PixelBiotech GmbH. Our solution provides you with a unique, precise, and comprehensive combination of RNA FISH (fluorescence in situ hybridization) probes and automated analysis equipment, allowing for the detection and quantification of the virus in samples.

Ikaros becomes even more intelligent! The next generation of the karyotyping system will bring artificial intelligence into the routine. New classifiers, trained with deep learning methods, take care of the tedious part of analysis preparation.

Neon is the brand new system for cytogenetic case and image data organization. Elaborated data management strategies, several convenient display modes, and many options for selecting and filtering content make Neon the perfect basis to organize large quantities of heterogeneous information.

Metafer, Ikaros, and Isis are the systems of choice for innovative, efficient, and fast analysis of human, plant, and animal samples. Trainable chromosome classifiers, a large
number of pre-defined karyogram forms for various species,and the innovative karyogram  editor make the system ready to be used with samples from numerous species.

DMI (Direct Multiplex Imaging) is the combination of a novel DNA-based multiplex hybridization technology and automatic imaging. DMI enables fast, specific and reproducible identification of multiple pathogenic microorganisms directly from samples without an additional culture, providing the necessary information for timely
decisions and a targeted antibiotic therapy.

MetaSystems has designed a system of hybridization and imaging tools to be integrated in the routine workflow of the pathology lab. Core of this system is the combination of dedicated DNA probes for tissue sections with the innovative platform Neon Metafer, a flexible and robust slide scanning system with many options.

Standardization is a highly important goal in the design of pre-clinical toxicology tests. The slide scanning platform Metafer has proven to be the most versatile and reliable tool to automate the analysis of OECD compliant tests like the erythrocyte micronucleus test (#474,1997), the in vitro micronucleus test (#487, 2004), the in vivo mammalian alkaline Comet assay (#489, 2014), and the chromosome aberration test (#473, 1997).

In combination with our CoolCube digital camera and state-of-the- art analysis software, Metafer - our fully automated slide scanning system - is the perfect solution for pharmaceutical toxicology laboratories and affiliated Contract Research Organizations (CROs).

Metafer is a highly versatile slide scanning platform, which bears many advantages for the setup of high-throughput routine Comet assay workflows.

Circulating Tumor Cells (CTCs) are cancer cells shed from primary or metastatic solid tumors into peripheral blood. Enumeration and characterization of these rare cells holds promise as a non-invasive means of detecting, diagnosing, and monitoring cancers. The Cytelligen SE-i•FISH® kit uses an unbiased approach called subtraction enrichment (SE), which combines non-haemolytic removal of red blood cells and immuno-magnetic removal of white blood cells to enrich for CTCs. The Metafer CTC Application was developed to detect CTCs processed by SE-i•FISH®, and analyze these within a clinically relevant time frame.

The slide scanning platform Metafer of MetaSystems has been acknowledged as the most reliable, and the fastest system to automate scoring of dicentric chromosomes, micronuclei, and foci in biodosimetry assays. Due to its flexible architecture, Metafer analyzes samples of all assays on the same hardware platform.

Sperm cell detection is a widely used forensic analysis tool in the investigation of sexual assault crimes. MetaSystems has developed a new Deep Neural Network (DNN) algorithm, which brings the advantage of Artificial Intelligence into the automated sperm detection domain.

The compelling diversity of diatoms, but also their importance for environmental monitoring makes it desirable to have an automated, simple, and fast solution for imaging and archiving of diatom samples. Since diatoms have a distinct three dimensional structure, imaging at high magnifications should also involve the acquisition of focus stacks.

With more than 30 years of innovation in digital imaging analysis and automation, MetaSystems is proud to announce the next generation of Metaphase detection and analysis. Our complete AI powered workflow facilitates the entire tedious process of finding metaphases straight to completed karyograms for review. Metaphase scanning and image quality has been made even faster with our Ultra High-Resolution CoolCube 4 camera.

White blood cells (WBCs) differential count is a widely performed hematological test for blood cancers diagnostic, inflammation and infection diseases detection. MetaSystems has developed a new algorithm based on a Deep Neural Network (DNN), and trained with thousands of pre-classified data, for an AI-assisted classification of WBCs.

The analysis and quantification of micronuclei in vitro is a  widely performed test for fast detection of DNA  damage in cells exposed to ionizing radiation or genotoxic chemical agents. MetaSystems has developed a  new Deep  Neural  Network  (DNN) algorithm, trained with thousands of pre-classified data, which brings the advantages of Artificial Intelligence to the detection of MN cells on Giemsa-stained slides.