Direct identification of bacteria from native respiratory samples without prior culture
Hospital-acquired pneumonia (HAP) is one of the most dangerous bacterial infections. HAP often affects critically ill patients and is responsible for a significant percentage of the developing sepsis cases. To avert such adverse health effects by HAP, treatment with appropriate antibiotics must be initiated promptly. This requires rapid identification of the pneumonia causing microorganisms.
The Respiratory DMI Kit supports quick antibiotic therapy decisions as it provides identification results directly from native respiratory patient samples such as sputum, endotracheal or bronchial aspirates without prior bacterial culture.
The assay design of 12 genus and species-specific probes enables easy, precise and reproducible identification of clinically relevant pathogens associated with the development of HAP and ventilator-associated pneumonia (VAP) within 35 minutes. Slides can be read manually or automatically scanned and imaged with the Metafer DMI Scanner.
Gram negative bacteria |
Gram positive bacteria |
|---|---|
| Acinetobacter spp. | Staphylococcus spp. |
| Enterobacteriaceae | Staphylococcus aureus |
| Escherichia coli | Streptococcus spp. |
| Haemophilus influenzae | Streptococcus pneumoniae |
| Klebsiella pneumoniae | |
| Pseudomonas aeruginosa | |
| Serratia marcescens | |
| Stenotrophomonas maltophilia |
Gram stains, together with rapid DMI results, provide timely, strong, reliable and cost-effective support for antibiotic selection with valuable information about the principle bacteria associated with nosocomial pneumonia (HAP / VAP). Moreover, DMI has the important advantage over other molecular diagnostics of preserving cell morphology, allowing phenotypic examination.
Early HAP / VAP pathogen identification provides significant cost-savings potential because it supports the timely selection of appropriate antibiotics based on commonly known resistance characteristics. And the swift selection of further specific tests for identified pathogens, such as resistance assays for S. aureus, can reduce unnecessary concomitant treatment costs and saves time and resources.
| Name | Order number | Size |
| Respiratory DMI Kit | P-7510-011-IG | The kit includes required reagents and consumables for 72 assays |
With almost 100 guests, the 2019 MetaSystems Distributor Meeting (DM) held last week in Heidelberg, Germany has been the biggest in history. In 2002, the MetaSystems DM has been established as an annual event ...
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