About 100 guests from 36 countries met on the XVIII. MetaSystems Distributor Meeting (DM) in November to exchange experiences and to get to know new trends and developments at MetaSystems.
Bacteremia DMI Kit
Evidence for Targeted Therapy
Analysis of positive blood cultures for the identification of the most relevant bacteremia-causing bacteria
Bacteremia is one of the most frequent hospital-acquired infections (HAIs). Resultant sepsis and septic shock mandate early intervention because survival rates decrease dramatically by every hour of delayed antibiotic treatment. Initial therapy relies on broad-band antibiotics until the pathogenic microorganisms can be identified. But broad-band antibiotics are often ineffective and contribute to surging bacterial resistance.
Fast pathogen identification, together with information about patient history and resistance incidence, is key for rapid and appropriate adaption of antimicrobial therapy for best patient outcomes – as well as to restrict accelerating antibiotic resistance.
Direct Multiplex Imaging (DMI) enables pathogen identification from mono- and polymicrobial positive blood culture (pBC) within 35 minutes. The assay with 12 genus and species-specific probes enables easy, precise and reproducible identification of over 90% of the bacteremia-relevant pathogens. Slides can be read manually or automatically scanned and imaged with the Metafer DMI Scanner.
Gram negative bacteria
Gram positive bacteria
|Acinetobacter spp.||Enterococcus faecalis|
|Escherichia coli||Staphylococcus aureus|
|Klebsiella pneumoniae||Staphylococcus spp.|
|Proteus mirabilis||Streptococcus pneumoniae|
|Pseudomonas aeruginosa||Streptococcus spp.|
With More Information
Gram stains, together with the rapid DMI results, provide strong, reliable and cost-effective guidance for antibiotic selection with valuable information about bacteremia causing pathogens. Moreover, DMI has the important advantage over other molecular diagnostics of preserving cell morphology, allowing phenotypic examination and viability assessment.
At Reduced Costs
Due to the labor-saving effects of the straightforward identification protocols, DMI facilitates routine work-up procedures for pBC bottles. Additional tests - such as resistance assays for S. aureus - can be ordered for identified pathogens and contaminated samples can be excluded, thus adding to the cost-efficiency and effectiveness of laboratory operations.
|Bacteremia DMI Kit||P-7510-010-IG||The kit includes required reagents and consumables for 72 assays|
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