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The film “Pleasantville”, starring Tobey Maguire and Reese Witherspoon, utilizes the gradual shift from the black and white layout typical of 1950s films to the bright colors of "modern" film. In the movie, the color change represents progress. At MetaSystems, too, colors brought unimagined progress in 1998 with the introduction of the first FISH probes. From these humble beginnings, our sister company MetaSystems Probes has emerged, offering a multifaceted and ever-growing portfolio of DNA and RNA probes.